Cyclebase 3.0

Cell-cycle regulation database

FHL1 [YPR104C]

Pre-rRNA-processing protein FHL1; Regulator of ribosomal protein (RP) transcription; has forkhead associated domain that binds phosphorylated proteins; recruits coactivator Ifh1p or corepressor Crf1p to RP gene promoters; also has forkhead DNA-binding domain though in vitro DNA binding assays give inconsistent results; computational analyses suggest it binds DNA directly at highly active RP genes and indirectly through Rap1p motifs at others; suppresses RNA pol III and splicing factor prp4 mutants

Synonyms:  FHL1,  FHL1p,  P39521,  P39521p,  P8283.15 ...

Linkouts:  STRING  UniProt