Cyclebase 3.0

Cell-cycle regulation database

NHP6A [YPR052C]

Non-histone chromosomal protein 6A; High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to chromosomes; functionally redundant with Nhp6Bp; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6A has a paralog, NHP6B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress

Synonyms:  NHP6A,  NHP6Ap,  P11632,  NHPA,  P11632p ...

Linkouts:  STRING  UniProt