Cyclebase 3.0

Cell-cycle regulation database

HST2 [YPL015C]

Cytoplasmic NAD(+)-dependent protein deacetylase; deacetylation targets are primarily cytoplasmic proteins; member of the silencing information regulator 2 (Sir2) family of NAD(+)-dependent protein deacetylases; modulates nucleolar (rDNA) and telomeric silencing; possesses NAD(+)-dependent histone deacetylase activity in vitro; contains a nuclear export signal (NES); function regulated by its nuclear export; Belongs to the sirtuin family. Class I subfamily.

Synonyms:  HST2,  HST2p,  P53686,  LPA2C,  P53686p ...

Linkouts:  STRING  UniProt