Cyclebase 3.0

Cell-cycle regulation database

NCR1 [YPL006W]

Niemann-Pick type C-related protein 1; Vacuolar membrane protein; transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; cells lacking Ncr1p exhibit high levels of long chain bases (LCB), similar to the accumulation of high amounts of lipids observed in patients with Neimann-Pick C, a disease caused by loss-of-function mutations in NPC1, the functional ortholog of Ncr1p

Synonyms:  NCR1,  NCR1p,  Q12200,  Q12200p,  YPL006W ...

Linkouts:  STRING  UniProt