Cyclebase 3.0

Cell-cycle regulation database

RAT1 [YOR048C]

Ribonucleic acid-trafficking protein 1; Nuclear 5' to 3' single-stranded RNA exonuclease; involved in RNA metabolism, including rRNA and snoRNA processing, as well as poly (A+) dependent and independent mRNA transcription termination; required for cotranscriptional pre-rRNA cleavage; displaces Cdk1p from elongating transcripts, especially as RNAPII reaches the poly(A) site, negatively regulates phosphorylation of the CTD of RNAPII, and inhibits RNAPII transcriptional elongation

Synonyms:  RAT1,  RAT1p,  Q02792,  HKE1,  Q02792p ...

Linkouts:  STRING  UniProt