Cyclebase 3.0

Cell-cycle regulation database

EXO1 [YOR033C]

Exodeoxyribonuclease 1; 5'-3' exonuclease and flap-endonuclease; involved in recombination, double-strand break repair, MMS2 error-free branch of the post replication (PRR) pathway and DNA mismatch repair; role in telomere maintenance; member of the Rad2p nuclease family, with conserved N and I nuclease domains; relative distribution to the nucleus increases upon DNA replication stress; EXO1 has a paralog, DIN7, that arose from the whole genome duplication

Synonyms:  EXO1,  EXO1p,  P39875,  DHS1,  OR26.23 ...

Linkouts:  STRING  UniProt