DNL4 [YOR005C]
Polydeoxyribonucleotide synthase [ATP] 4; DNA ligase required for nonhomologous end-joining (NHEJ); forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth; mutations in human ortholog lead to ligase IV syndrome and Dubowitz syndrome; Belongs to the ATP-dependent DNA ligase family.
Synonyms: DNL4, DNL4p, Q08387, LIG4, Q08387p ...