LTO1 [YNL260C]
Uncharacterized ORAOV1 family protein YNL260C; Essential protein that forms a complex with Rli1p and Yae1p; ortholog of human ORAOV1, which is overexpressed in solid tumors; inviability of null mutant under standard conditions is complemented by overexpression of ORAOV1; essential for growth under standard (aerobic) conditions but not under anaerobic conditions; may have a role in protection of ribosomal assembly and function from damage due to reactive oxygen species; Belongs to the ORAOV1 family.
Synonyms: LTO1, LTO1p, YNL260C, P53846, YNL260Cp ...