TIS11 [YLR136C]
Cysteine-three-histidine protein 2; mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; TIS11 has a paralog, CTH1, that arose from the whole genome duplication
Synonyms: TIS11, TIS11p, P47977, CTH2, L3143 ...