Cyclebase 3.0

Cell-cycle regulation database

TRX1 [YLR043C]

Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx2p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases iunder DNA replication stress; TRX1 has a paralog, TRX2, that arose from the whole genome duplication

Synonyms:  TRX1,  TRX1p,  P22217,  P22217p,  TRX2 ...

Linkouts:  STRING  UniProt