Cyclebase 3.0

Cell-cycle regulation database

RAD5 [YLR032W]

Radiation sensitivity protein 5; DNA helicase/Ubiquitin ligase; involved in error-free DNA damage tolerance (DDT), replication fork regression during postreplication repair by template switching, error-prone translesion synthesis; promotes synthesis of free and PCNA-bound polyubiquitin chains by Ubc13p-Mms2p; forms nuclear foci upon DNA replication stress; associates with native telomeres, cooperates with homologous recombination in senescent cells; human homolog HLTF can complement yeast null mutant

Synonyms:  RAD5,  RAD5p,  P32849,  P32849p,  REV2 ...

Linkouts:  STRING  UniProt