Cyclebase 3.0

Cell-cycle regulation database

MIA40 [YKL195W]

Import and assembly protein in mitochondrial intermembrane space; component of MIA pathway which mediates import and oxidative folding of substrates including small proteins containing twin cysteine motifs; acts in concert with Erv1p, which oxidizes the cysteine residues of Mia40p to comprise a disulfide relay system that catalyzes import; also mediates folding of Atp23p via a chaperone-like activity; forms a dimer that binds iron-sulfur cluster in vitro

Synonyms:  MIA40,  MIA40p,  P36046,  P36046p,  TIM40 ...

Linkouts:  STRING  UniProt