Cyclebase 3.0

Cell-cycle regulation database

NUC1 [YJL208C]

Major mitochondrial nuclease; has RNAse and DNA endo- and exonucleolytic activities; roles in mitochondrial recombination, apoptosis and maintenance of polyploidy; involved in fragmentation of genomic DNA during PND (programmed nuclear destruction); encodes ortholog of mammalian endoG; Belongs to the DNA/RNA non-specific endonuclease family.

Synonyms:  NUC1p,  P08466,  HRE329,  J0310,  P08466p ...

Linkouts:  STRING  UniProt