Cyclebase 3.0

Cell-cycle regulation database

RRD1 [YIL153W]

Peptidyl-prolyl cis/trans-isomerase; activator of the phosphotyrosyl phosphatase activity of PP2A; involved in G1 phase progression, microtubule dynamics, bud morphogenesis and DNA repair; required for rapid reduction of Sgs1p levels in response to rapamycin; subunit of the Tap42p-Sit4p-Rrd1p complex; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; Belongs to the PTPA-type PPIase family.

Synonyms:  RRD1,  RRD1p,  P40454,  NCS1,  P40454p ...

Linkouts:  STRING  UniProt