Cyclebase 3.0

Cell-cycle regulation database

ERV1 [YGR029W]

Essential for respiration and vegetative growth protein 1; Flavin-linked sulfhydryl oxidase of the mitochondrial IMS; N-terminus is an intrinsically disordered domain that in the cytosol helps target Erv1p to mitochondria, and in the intermembrane space oxidizes Mia40p as part of a disulfide relay system that promotes intermembrane space retention of imported proteins; functional ortholog of human GFER (ALR); human GFER carrying N-terminal 21 amino acids of Erv1p functionally complements the lethality of the erv1 null mutation

Synonyms:  ERV1,  ERV1p,  P27882,  P27882p,  YGR029W ...

Linkouts:  STRING  UniProt