Cyclebase 3.0

Cell-cycle regulation database

PKP2 [YGL059W]

Mitochondrial protein kinase; negatively regulates activity of the pyruvate dehydrogenase complex by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp1p and phosphatases Ptc5p and Ptc6p; relocalizes from mitochondrion to cytoplasm upon DNA replication stress

Synonyms:  PKP2,  PKP2p,  P53170,  P53170p,  YGL059W ...

Linkouts:  STRING  UniProt