ISD11 [YER048W-A]
Iron-sulfur protein biogenesis, desulfurase-interacting protein 11; Cysteine desulfurase (Nfs1p) activator; essential for the formation of the persulfide intermediate at the desulfurase active site during pyridoxal phosphate-dependent desulfuration of cysteine; required for mitochondrial iron-sulfur cluster biosynthesis; exclusive to eukaryotes, implicated as eukaryotic supplement to the bacterium-derived Fe-S cluster (ISC) assembly apparatus; involved in regulation of iron metabolism; member of the LYR protein family
Synonyms: ISD11, ISD11p, Q6Q560, Q6Q560p, YER048W-A ...