Cyclebase 3.0

Cell-cycle regulation database

AFG3 [YER017C]

Mitochondrial respiratory chain complexes assembly protein AFG3; Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; involved in cytoplasmic mRNA translation and aging; expression of human homolog AFG3L2 can complement yeast yta12 afg3 double mutant; In the N-terminal section; belongs to the AAA ATPase family.

Synonyms:  AFG3,  AFG3p,  P39925,  P39925p,  YER017C ...

Linkouts:  STRING  UniProt