Cyclebase 3.0

Cell-cycle regulation database

UGO1 [YDR470C]

Outer membrane component of the mitochondrial fusion machinery; binds to Fzo1p and Mgm1p to link these two GTPases during mitochondrial fusion; involved in fusion of both the outer and inner membranes; facilitates dimerization of Fzo1p during fusion; import into the outer membrane is mediated by Tom70p and Mim1p; has similarity to carrier proteins but likely not a transporter; similar to human SLC25A46 implicated in optic atroprophy spectrum disorder

Synonyms:  UGO1,  UGO1p,  Q03327,  Q03327p,  YDR470C ...

Linkouts:  STRING  UniProt