TOM1 [YDR457W]
Temperature-dependent organization in mitotic nucleus protein 1; E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators; involved in degradation of excess histones; interacts with Dia2p and is required for Dia2p degradation; required to target Cdc6p for ubiquitin-mediated destruction during G1 phase; Belongs to the UPL family. TOM1/PTR1 subfamily.
Synonyms: TOM1, TOM1p, Q03280, D8035.1, Q03280p ...