SYF1 [YDR416W]
Synthetic lethal with CDC40 protein 1; Member of the NineTeen Complex (NTC); that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; null mutant has splicing defect and arrests in G2/M; relocalizes to the cytosol in response to hypoxia; homologs in human and C. elegans
Synonyms: SYF1, SYF1p, Q04048, NTC90, Q04048p ...