Cyclebase 3.0

Cell-cycle regulation database

YPR1 [YDR368W]

Putative reductase 1; NADPH-dependent aldo-keto reductase; reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases; protein abundance increases in response to DNA replication stress; YPR1 has a paralog, GCY1, that arose from the whole genome duplication; human homolog AKR1B1 can complement yeast null mutant

Synonyms:  YPR1,  YPR1p,  Q12458,  D9481.8,  Q12458p ...

Linkouts:  STRING  UniProt