SIR4 [YDR227W]
Silent information regulator 4; SIR protein involved in assembly of silent chromatin domains; silent information regulator (SIR) along with SIR2 and SIR3; involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; some alleles of SIR4 prolong lifespan; required for telomere hypercluster formation in quiescent yeast cells
Synonyms: SIR4, SIR4p, E9P9V6, P11978, E9P9V6p ...