Cyclebase 3.0

Cell-cycle regulation database

DPB4 [YDR121W]

Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex; involved in both chromosomal DNA replication and inheritance of telomeric silencing; stabilizes the interaction of Pol epsilon with primer-template DNA, positively affecting the processivity of the polymerase and exonuclease activities of Pol epsilon; interacts with extranucleosomal DNA and acts as anchor point for ISW2 complex that retains its position on DNA during nucleosome mobilization

Synonyms:  DPB4,  DPB4p,  Q04603,  Q04603p,  YDR121W ...

Linkouts:  STRING  UniProt