DOA4 [YDR069C]
Ubiquitin-specific-processing protease 4; Ubiquitin hydrolase; deubiquitinates intralumenal vesicle (ILVs) cargo proteins; required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins destined for the vacuole; DOA4 has a paralog, UBP5, that arose from the whole genome duplication; Belongs to the peptidase C19 family.
Synonyms: DOA4, DOA4p, P32571, D4270, DOS1 ...