Cyclebase 3.0

Cell-cycle regulation database

NUS1 [YDL193W]

Forms dehydrodolichyl diphosphate syntase complex with RER2 or SRT1; tet-repressible mutant shows accumulation of hypoglycosylated forms of CPY, suggesting that Nus1p may be involved in protein trafficking; mutations in human homolog NUS1 have been implicated in congenital scoliosis, neurological impairment, refractory epilepsy, hearing deficit, and visual impairment; human cis-prenyltransferase complex complements yeast null mutant

Synonyms:  NUS1,  NUS1p,  Q12063,  D1239,  Q12063p ...

Linkouts:  STRING  UniProt