CDC9 [YDL164C]
Polydeoxyribonucleotide synthase [ATP] 1; DNA ligase I found in nucleus and mitochondria; essential enzyme that joins Okazaki fragments during DNA replication; also acts in ribonucleotide excision repair, base excision repair, and recombination; DNA ligase I mutants trigger ubiquitination of PCNA at K107, facilitating Rad59p-mediated bypass of unligated Okazaki fragments; human homolog LIG1 can complement yeast cdc9 temperature-sensitive mutant at restrictive temperature; Belongs to the ATP-dependent DNA ligase family.
Synonyms: CDC9, CDC9p, P04819, P04819p, YDL164C ...