THI3 [YDL080C]
Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; Regulatory protein that binds Pdc2p and Thi2p transcription factors; activates thiamine biosynthesis transcription factors Pdc2p and Thi2p by binding to them, but releases and de-activates them upon binding to thiamine pyrophosphate (TPP), the end product of the pathway; has similarity to decarboxylases but enzymatic activity is not detected
Synonyms: THI3, THI3p, Q07471, KID1, Q07471p ...