Cyclebase 3.0

Cell-cycle regulation database

HCM1 [YCR065W]

High-copy suppressor of calmodulin protein 1; Forkhead transcription factor; drives S-phase activation of genes involved in chromosome segregation, spindle dynamics, budding; also activates genes involved in respiration, use of alternative energy sources (like proline), NAD synthesis, oxidative stress resistance; key factor in early adaptation to nutrient deficiency and diauxic shift; suppressor of calmodulin mutants with specific SPB assembly defects; ortholog of C. elegans lifespan regulator PHA-4

Synonyms:  HCM1,  HCM1p,  P25364,  P25364p,  YCR065W ...

Linkouts:  STRING  UniProt