Cyclebase 3.0

Cell-cycle regulation database

ALK2 [YBL009W]

Serine/threonine-protein kinase Haspin homolog ALK2; Protein kinase; along with its paralog, ALK1, required for proper spindle positioning and nuclear segregation following mitotic arrest, proper organization of cell polarity factors in mitosis, proper localization of formins and polarity factors, and survival in cells that activate spindle assembly checkpoint; phosphorylated in response to DNA damage; ALK2 has a paralog, ALK1, that arose from the whole genome duplication; similar to mammalian haspins

Synonyms:  ALK2,  ALK2p,  P32789,  P32789p,  YBL009W ...

Linkouts:  STRING  UniProt

G1SG2MRank: 192Expression
PTMs
NameSourceEvidence
Cdc28 substrateLoog et al 2005High-throughput
CDK substrateRegex[ST]P.[RK]
Complexes
No evidences in this channel